Does celebrex prevent progression of RA like Enbrel does. I am very uncofortable taking enbrel and wonder if celebrex will do sort of the same thing.
Every week it is getting harder to take the injection. I just can't see myself doing this for long term. It doesn't even feel like it is helping, maybe even making me worse.
Naproxen put me into remmision for a while, and it seems like celebrex is the same kind of drugs.
Anyone on it that can give me some answers?
Thanks!
No; their both anti-inflammatories and although they will reduce some of the inflammation that causes the pain they won't do anything to prevent joint damage or slow the progression.
What other medications have you been on? There are a lot of DMARDS out there they might be an option. I don't know how bad off you are.....likely pretty bad if your doctor has started Enbrel. I went years before using a biologic but I did use a DMARD since the dx'ed and it's definately slowed the progression and gotten me through all the years without too much damage.
It's pretty important that you take something like that.
Celebrex is an NSAID. it is used for inflamation, pain and stiffness. It DOESNT stop or slow the disease progression. It doesnt affect joint erosion.hmmm...yeah lovie it is so funny that you say that i must have been pretty bad. I wasn't! When I went to see him I had some minor knee pain and wrist pain. I could deal with it with out taking meds. I told him about when I was younger and that first time her wanted to put me on enbrel. Didn't even have my blood work or past records. That;s why I feel so uncomfotable taking it.
Since I started I went from minor pain to can't get out of my car! So frustrating.
Yeah; I'm not sure I'd like that Christina.
I went more than 10 years without a biologic. I agree with hitting it hard and preventing joint damage but there are a lot of Disease modifying medications that should be tried first in my opinion.
Have you ever taken anything like Sulfersalizine? Plaquinel? Methotrexate? If not I'd have to wonder why. These medications often are enough to slow things down and buy you a lot of time. I always felt liek it was best to say the bigger guns for down the road. This disease only progresses. You need to use the weaker medication as long as possible and work your way up. At least that's my theroy. My doctors as well. I've had three RD's in 13 years. All seem to agree that was what was best for me. Mine started out at mild/moderate then went to moderate and now seem to be fairly mild. Thanks to Humira and MTX I seem to be in somewhat of a remission. I've even stopped Humira and manage really well. Many aren't are lucky as me though.
Maybe some other's will chime in about this. I hope so.
YES! I feel the same way! What if I get worse and then what? I have nothing to turn to. I know I don't want to be on MTX. I don't even know enough about the other ones. I will do some research right now. I got back to the doc on the 20th. I hate that I started enbreland now I don't want to keep taking it. I hope others will chime in too. I have been going crazy about this for weeks now. Thanks for your help.That's the first DMARD I took and I guess I took it for about two years before changing to plaquinel. It's fairly mild but worked good for me.
Definately ask your doctor about it and other options as well. You have a choice....don't let them tell you that you don't. If you want to stop Enbrel make that clear to the doctor. You need to get the doctor to where he's letting you help in the decisions as far as your treatment is concerned. Once he sees that you are researching things and know your stuff he'll respect your opinion.
The way you are thinking is correct. For me I've worked my way up to stronger medications. When the weaker ones stop working then you start the stronger ones. Over time things stop working....at least that's been my experience.
Thanks Ashley that is good advice. Did you have any weird side effects on it? There doesn't seem to be too many. And if I can quit these injections that would be great. Chrisitna- I started out arthrotec and then sulphasalazine then onto mtx and gold then onto biologics( humira and now enbrel). It depends on how far your RA has progressed as to what meds your rheumy thinks you should go onto but your input is crucial too. I went for years on the not so strong meds and coped just fine, then i stopped taking them cause i thought i knew betterI just didn't quite beleive them when they told me I would have to take medication for the rest of my life. I thought "I'm cured, I don't need meds at all" Lesson learned I guess.
Sulfersalizine didn't seem to have any side effects for me. Once I got a horrible sun burn and I do think that was related but besides that none at all. Some people are highly allergic to sulfer. If you don't know if you are or not you'll find out pretty quick when you start taking it. I think it's pretty rare though.
sulphasalazine is a biologic right? At least that is what I have read.
I think the doctor saw my hands and feet (which are pretty disformed) and it freaked him out. I kept trying to tell him that they have been like that since I was 10 with no changes.
I am going to ask him to take xrays to see what damage has been done. I don't even have any signs in my blood that I have RA. EVERYTHING is normal.
The thing that scares me the most about enrel is the risk of cancer. I already have cancer in my family. If it block these TNF's and I have a normal amount...who knows what could happen. I can't wait to get to the doc on the 20th. This is drving me INSANE.
No; sulfersalizine is considered a DMARD. The biologics are the injectables like Enbrel, Humira and there are a few other's too.
Make sure you mention your family history of cancer and your concern there.
[QUOTE=cah1418] Anyone on it that can give me some more info...issues you have had or concerns?[/QUOTE]
I've been taking sulfasalazine for a few years now. Not sure how effective it is (on it's own) since I take it with other meds. The only problem I had when I started it, was headaches. But I found that drinking a lot of water through the day seemed to help.
[QUOTE=Lovie]No; sulfersalizine is considered a DMARD. The biologics are the injectables like Enbrel, Humira and there are a few other's too.
[/QUOTE]
I have had this disease for 10 years and i know nothing! I guess I was young. I am starting to learn now.
What is the difference. They both modify the disease right? So they are both considered DMARD's but enbrel is a biologic? Is the only difference that they are injectible?
Sorry for all of the questions!
I started Sulfasalazine about 2 months ago and so far haven't noticed any changes. I've had no reaction to it except for orange tinged urine.
Have been having lots of muscle, joint, and tendon pain for the last couple of months. My RD changed my biophos. to Actonel and I did a little research and found out that in 19-21% of patients who take Actonel that there is an increase in muscle, joint, and tendon pain. I stopped taking it 2 weeks ago and I have had a dramatic decrease in symptoms. I'll try to get extra Calcium, diet, and exercise and hopefully that will help the bone density issue. My RD changed my biologics from Remicade to Humira because of the increased pain and inflammation and added Sulfasalzine as an additional DMARD. I wouldn't have had to change biologics or had Sulfas. added if he had recognized the side effect of Actonel. Please be sure to mention to your RD an increase in symptoms if you're on any of the biophos. such as Actonel, Boniva, Fosomax, etc. The increase in pain may be due to the biophos. and should be addressed. Lindy
I just went over Sulf again with our ped rheum. Another doctor told us she never uses it because of the risk of Stehpens Johnson Syndrome, which is the allergic reaction to the sulfa.I'm not sure I can explain the differences between medications like Sulfersalizine and Enbrel. Yes; they do both slow the progression of the disease but biologics work differently and are in a different class of drug.
I hope I'm not telling you the wrong thing.....but this is my understanding of it all.
Sulphasalazine is an anti inflamatory and the biologics are TNF ( Tumour necrosis factor) blockers. It is a protein that blocks how much TNF we produce. ( people with RA can produce too much TNF) this will therefore stop the progression of the disease.
I think this is right.
ok I think that makes sense. I will ask the doctor when I see him.
No: Sulfersalizine is not an anti-inflammatory. It's a DMARD not an NSAID. I know that for sure.
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anyone see that episode of house where the guy turned orange? Wth the way I react to meds, I could see not just my urine turning orange, but my whole body! haha
So is this a steriod? I an finding conflicting information. Anyone know for sure?
Well it looks like from that we're both right. I didn't realize that.
No; it's not a steriod. BUT then again I didn't realize it was an anti-inflammatory either so you better look a little deeper than what I know. lol
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