What Probiotics Do | Arthritis Information

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I got this from wikipedia http://en.wikipedia.org/wiki/Probiotic

Experiments into the benefits of probiotic therapies suggest a range of potentially beneficial medicinal uses for probiotics. For many of the potential benefits, research is limited and only preliminary results are available. It should be noted that the effects described are not general effects of probiotics. All effects can only be attributed to the strain(s) tested, not to the species, nor to the whole group of LAB (or other probiotics).[16]

Managing Lactose Intolerance

As lactic acid bacteria actively convert lactose into lactic acid, ingestion of certain active strains may help lactose intolerant individuals tolerate more lactose than what they would have otherwise.[4] In practice probiotics are not specifically targeted for this purpose, as most are relatively low in lactase activity as compared to the normal yogurt bacteria.

Prevention of Colon Cancer

In laboratory investigations, some strains of LAB have demonstrated anti-mutagenic effects thought to be due to their ability to bind with heterocyclic amines; carcinogenic substances formed in cooked meat.[17] Animal studies have demonstrated that some LAB can protect against colon cancer in rodents, though human data is limited and conflicting.[18] Most human trials have found that the strains tested may exert anti-carcinogenic effects by decreasing the activity of an enzyme called β-glucuronidase[18] (which can generate carcinogens in the digestive system). Lower rates of colon cancer among higher consumers of fermented dairy products have been observed in some population studies.[4]

Cholesterol Lowering

Animal studies have demonstrated the efficacy of a range of LAB to be able to lower serum cholesterol levels, presumably by breaking down bile in the gut, thus inhibiting its reabsorption (which enters the blood as cholesterol). Some, but not all human trials have shown that dairy foods fermented with specific LAB can produce modest reductions in total and LDL cholesterol levels in those with normal levels to begin with, however trials in hyperlipidemic subjects are needed.[4]

Lowering Blood Pressure

Several small clinical trials have shown that consumption of milk fermented with various strains of LAB can result in modest reductions in blood pressure. It is thought that this is due to the ACE inhibitor-like peptides produced during fermentation.[4]

Improving Immune Function and Preventing Infections

LAB are thought to have several presumably beneficial effects on immune function. They may protect against pathogens by means of competitive inhibition (i.e., by competing for growth) and there is evidence to suggest that they may improve immune function by increasing the number of IgA-producing plasma cells, increasing or improving phagocytosis as well as increasing the proportion of T lymphocytes and Natural Killer cells.[19][20] Clinical trials have demonstrated that probiotics may decrease the incidence of respiratory tract infections[21] and dental caries in children[22] . LAB foods and supplements have been shown to be effective in the treatment and prevention of acute diarrhea; decreasing the severity and duration of rotavirus infections in children as well as travelers diarrhea in adults.[19][20]

Helicobacter pylori

LAB are also thought to aid in the treatment of Helicobacter pylori infections (which cause peptic ulcers) in adults when used in combination with standard medical treatments.[23]

Antibiotic-associated diarrhea

A meta-analysis suggested probiotics may reduce antibiotic-associated diarrhea. [24] A subsequent randomized controlled trial also found benefit in elderly patients. [25]

Reducing Inflammation

LAB foods and supplements have been found to modulate inflammatory and hypersensitivity responses, an observation thought to be at least in part due to the regulation of cytokine function.[19] Clinical studies suggest that they can prevent reoccurrences of inflammatory bowel disease in adults,[19] as well as improve milk allergies[26] and decrease the risk of atopic eczema in children.[27]

Improving Mineral Absorption

It is hypothesized that probiotic lactobacilli may help correct malabsorption of trace minerals, found particularly in those with diets high in phytate content from whole grains, nuts, and legumes.[28]

Prevents Harmful Bacterial Growth Under Stress

In a study done to see the effects of stress on intestinal flora, rats that were fed probiotics had little occurrence of harmful bacteria latched onto their intestines compared to rats that were fed sterile water.[29]

Irritable Bowel Syndrome and Colitis

B. infantis 35624, sold as Align, was found to improve some symptoms of irritable bowel syndrome in women in a recent study.[30] Another probiotic bacterium, Lactobacillus plantarum 299V, was also found to be effective in reducing IBS symptoms. [31] Additionally, a probiotic formulation, VSL3, was found to be effective in treating ulcerative colitis [32] Bifidobacterium animalis DN-173 010 may help. [33]

Well, that explains the stress conditons that got me into this boat.
 
Pip
P.S.  Probiotics won't kill you and may very well reduce your symptoms.  It MAY buy you more time on the traditonal meds.  Think about this, people, please.

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