Well after two doses of prednisone and almost 24 hours I feel a difference. I hurt but don't hurt excruciatingly. My knees are bothering me but I have done stairs about 8 times today and my fingers are hurting. Especially when holding stuff. So I feel like it is doing somethign and hopefully that means I will feel even better tomorrow. I do have a headache and just took Tylenol for the pain. Going to go take a nap and hopefully be rid of that soon. It will only get better !! That is really good after only 2 doses. I'm really glad