Accelerated Aging Among People With RA | Arthritis Information

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The observation that people with rheumatoid arthritis (RA) die at a younger age than people without this disease is not new, but arthritis experts don't fully understand the causes of the increased mortality rates. Laboratory scientists have observed that RA and other diseases can cause multiple systems within the body to age more rapidly than expected. Cells affected by diseases begin to show signs of what's called accelerated aging -- damage at the molecular level resulting in poorer function. Mayo researchers attending the American College of Rheumatology Annual Meeting will share preliminary findings that suggest increased mortality among people with RA is consistent with the concept of accelerated aging.

"We've known for decades that the mortality rate among people with rheumatoid arthritis is higher, and that these patients are at increased risk for heart and lung disease," explains lead researcher and Mayo epidemiologist Sherine Gabriel, M.D. "With this study, we've now applied a mathematical model that shows consistency between our observed mortality rates and our understanding of the concept of accelerated aging."

Dr. Gabriel explains that new knowledge about this acceleration factor also underscores the need for people with RA to be aware of their increased health risks and to seek medical care that addresses their total health.

"Because rheumatoid arthritis is chronic and can be so consuming, patients and their doctors sometimes pay less attention to other issues, like cardiovascular health," notes Dr. Gabriel. "Studies like these remind us that early diagnosis and intervention are extremely important for these patients."

http://www.sciencedaily.com/releases/2006/11/061113170808.htmI am Not imagining it-- I have a lot of new wrinkles since stating mtx a few months ago.  I am turning 45 this summer but the wrinkles seemed to happen overnight.  When I smile I see them like ripples across my cheeks.  That is depressing!  Pass the antioxidants!  Of course, I am 30 but lots of people still think I look like I'm in college.  But I've had a number of medical issues this year, moles removed, etc.I didn't have one gray hair before RA, in the first year "BOOM" a ton of gray hairs, this was age 32.

 
Now at 35, almost 36, I have the gray hair, puffy face from wear and tear, wrinkles and i just look down right older, I would rate me about 48 looking.
 
RA definately ages you.  not only wrinkles etc. but it wears your body down by overworking it.
A lot of the women in my family went gray in their 20s, my grandmother in particular (she just has OA, though, and had kids when she was 16, so I think that would contribute ;) )

It's interesting because I've always felt like I looked too young (I'm still 19 lol) but emotionally/mentally, I'm feel like a Crone/mother figure. I'm ready to find my soulmate and settle down for suuure--no drugs or clubbing for me, thanks :)

Deepak Chopra has this bit in his book "Unconditional Life" about the idea that aging, like everything else in the material world, is merely an illusion--we only age because we see others age--here's the quote,

"A master in India once said to his disciples, 'You have enclosed yourself in the prison of time and space, sqyeesing your experience into the span of a lifetime and the volume of a body. It is because of this self-imposed illusion that all of your conflicts arise: life and death, pain pleasure, hope and fear. To end those problems, you must first end the illusion.

But how is that done, a disciple asked.

The master replied, 'You are caught in this world like fish in a net. But all nets have holes. Find one, and excape through it, and you will see what reality actually is.'"

It's a really good book, I'm learning a lot about Hinduism and changing my self-perception along the way.
hi all i dont think the post is regarding ageing on the outside but
inside the body .. alltough it does affect everywere..

this is not good news espeially scince pred allso linked whith accelerated aging
i agree that we need one medical team to oversee the overall medical health
but seeing a gp rheumatologist nurses this may ever happen .

Boney

ps a cure for wrinkles.. buy a Iron   [QUOTE=Jodi_Girl]I am Not imagining it-- I have a lot of new wrinkles since stating mtx a few months ago.  I am turning 45 this summer but the wrinkles seemed to happen overnight.  When I smile I see them like ripples across my cheeks. 

I still say it's an individual thing.  I know my other sister (ten years younger than the RA sister) won't see this, so I can say it:  She looks OLDER than my RA sister and she doesn't have RA, just a bit of OA in the hands.  They have different bone structure of the face, but more important, my RA sister takes better care of herself.  There are many variables, but I agree, this article was talking more about aging internally, and that's really depressing.  But I choose to think that if my RA sister can make herself look younger than my OA sister externally, we can do the same internally by being vigilant about our healthcare.  Hey, there are exceptions to every rule and who's to say which of us will be that exception.  I intend to be one of them.  So there.

 

Hey no hoggin' at the pity party! I probably aged 10 years in the last one and I don't even have RA. And I feel it. 

LOL Mike!

Hmm... I haven't really noticed myself aging more. I don't think. Maybe I'm in denial. Hahaha! The silvers have been there and growing in numbers since I was about 10. I tell DH I'm going up in value.  wonderwoman    
 
what i have been taught  is it is all about the money.   you can't be too skinny and you can't have too much money.   that is not my motto.  but the family i was raised in is it is all about looks what you look like what you drive where you live blah blah blah.  needless to say we are the outcasts.  my husbands family is the same so we feel we don't belong.   what do you think is really important?   wonderwoman 
wonderwoman2008-05-15 20:20:12HI guys, the radiologist that reported my MRI of my spine when I was 23, told me I had the spine of a 70 year old woman, I guess now that I am 44, and my spine has worsened, I must have that of a 100yr old!!!!!  Who cares, I am here for a good time not a long time, LOL, Janie.

I certainly feel 100 some days!

Wonderwoman, of course what is inside is important.  I recently e-mailed an article someone posted here (I think) with regard to the dangers of Botox.  Since my sister has problems with convulsions now, I asked her to stop it.  She said it's too expensive anyway so she'll stop, though I know it will be hard for her.  It's all about looking young, to her.  Many people you see who you think look better than you have probably had some work done.  I just felt bad that you were being so hard on yourself.  I'd be willing to bet you look a lot better than you think you do.  We women have a tendency to be very critical of ourselves, especially our bodies.  I'll bet if I asked the women on this board if they were happy with the way they look, they'd come up with all sorts of complaints.  It's what we do. The truth is, we're all perfect! 
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