When a person develops a sore or a boil, it erupts, drawing to it immune system cells that fight the infection. Then it resolves and flattens into the skin, often leaving behind a mark or a scar.
A similar scenario plays out in the blood vessels. However, when there is a defect in the resolution response -- the ability of blood vessels to recover from inflammation -- atherosclerosis or hardening of the arteries can result, said researchers at Baylor College of Medicine in Houston and Harvard Medical School in Boston in a report that appears online June 18 in The Journal of the Federation of American Societies for Experimental Biology. The major factor in this disease is a deficiency in the chemical signals that encourage resolution (pro-resolution signals). These signals are produced in the blood vessel where the inflammation occurs, the researchers said.
Chronic inflammation of the artery wall can cause atherosclerosis, a major risk factor for heart disease and heart attack. However, said Dr. Lawrence C.B. Chan, professor of medicine and molecular and cellular biology and chief of the division of division of diabetes, endocrinology and metabolism at BCM, in many instances, the lesions or little sores inside the artery arise and then resolve, often from a very young age. The mystery is why some lesions do not heal.
http://www.sciencedaily.com/releases/2008/06/080618114609.htmHmmm Still high cholesterol has to play a role. My greatgrandmother died of this. My grandmothers was caught in time. I have inherited there high cholesterol. So i expect to have this problem later in life. This is interesting. But i must add that these two women had no other health problems in life except highcholesterol. The hardening of the ateries did not effect them until into there eighties.Actual thanks it all makes perfect sence to me now. It seems i am finding that high cholesterol meds have anti inflamatory actions. Well at least two that i know of.
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