I started taking methotextrate on May 24. I had my bloodwork done before I started mtx so my doctor has my baseline numbers. Money is tight right now ... what would be your suggestions as to when is the latest I should get my bloodwork done and still be safe? Thanks in advance.My doctor told me the MTX blood test must be done every 2 months. It might have been 1 time per month in the very beginning...Every 2 months. Some have it done every 3 months and some 2 months. I feel more comfortable every 2 months and my RD wants it done every 2 month. LindyI go every six weeksusually its every 2-3 months depending on dosage and personal health history but since you have just started you really should check with your doctor he may want it to be every month until he sees how you reactI do my bloodwork monthly, always have.Mine is every 8 weeks.Every two months for me. I've been on mtx for yearrrrrrrrrrs, and have labwork every 2 months. If your alt/sgpt (liver function test) is up or high, then your doc may want to adjust your meds or watch it more carefully for awhile. How often did your doc whatcha to have it done? wow thats a long time