http://www.fiercepharma.com/story/fda-puts-plavix-under-safety-review/2009-01-27?utm_medium=rss&utm_source=rss&cmp-id=OTC-RSS-FP0
From the article:
"Two types of patients may have trouble metabolizing Plavix, hampering its ability to prevent clotting, the Associated Press
reports. Patients using certain heartburn medications may get less
benefit from the drug because the gastro-meds can neutralize its
benefits. And particular gene variations may impede Plavix as well."
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