Direct Route from the Brain to the Immune System | Arthritis Information

 

Discalimer: this is a press release not a scientifically imbued article.

http://www.northshorelij.com/sitemaker/websitefiles/NorthSho7917635/template.cfm?xyzpdqabc=0&id=204&action=detail&ref=968

An excerpt:
[quote]With this new understanding of the vagus nerve’s role in regulating inflammation, scientists believe that they can tap into the body’s natural healing defenses and calm the sepsis storm before it wipes out its victims. Each year, 750,000 people in the United States develop severe sepsis, and 215,000 will die no matter how hard doctors fight to save them. Sepsis is triggered by the body’s own overpowering immune response to a systemic infection, and hospitals are the battlegrounds for these potentially lethal conditions.[/quote]


the vagle nerve!!  that's an issue for MANY Of my family members....  they faint dead away..

that sounds so interesting!! thanks, Shug!!   OMG>> am I going to use my Barnes & Noble gift card to get a book??? LOLhttp://www.nslij.com/body.cfm?id=9799
[quote]This work uncovered a method to prevent diseases caused by the immune system, which can overproduce molecules called cytokines. “Cytokine storm” causes the physiological and pathological effects of sepsis, rheumatoid arthritis and other inflammatory diseases.[/quote] he's written text books on the immune system as well Disclaimer: the following is from a blog.
>>here<< I cannot make a hot link for the URL, so... copy and paste the address: http://feinsteininstitute.typepad.com/feinsteinweblog/news_from_neuroimmunology.htm or maybe a web search?

Dr. Tracey and his colleagues discovered that a brain chemical called acetylcholine is summoned and floats a short distance to land on receptors of immune cells called macrophages, and this seems to shut off the massive immune response.
>>HERE<< is another provocative tidbit...
[quote]In diseases such as rheumatoid arthritis, tissue destruction by neutrophils may worsen disease progression. We hope that our studies will allow us to selectively switch off destructive capacity of neutrophils in inflammatory diseases. [/quote]
[QUOTE=Spelunker]Disclaimer: the following is from a blog.
>>here<< I cannot make a hot link for the URL, so... copy and paste the address: http://feinsteininstitute.typepad.com/feinsteinweblog/news_from_neuroimmunology.htm or maybe a web search?

Dr. Tracey and his colleagues discovered that a brain chemical called acetylcholine is summoned and floats a short distance to land on receptors of immune cells called macrophages, and this seems to shut off the massive immune response.
[/QUOTE] Babs, it is beyond my control Although specific to septic shock, this article compliments the other articles.

[quote]The action is pronounced: messenger RNAs (mRNAs) which are blueprints for very specific cytokines--namely interleukin-1 beta, tumor necrosis factor alpha and COX-2--are degraded. That process of degrading the mRNAs shuts off production of these cytokines.[/quote]

It is rather disappointing that these articles, for the most part, are not immediately current.

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