Key Culprits In Lupus Discovered | Arthritis Information

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ScienceDaily (June 30, 2009) — The more than 1.5 million Americans with systemic lupus erythematosus (or lupus) suffer from a variety of symptoms that flare and subside, often including painful or swollen joints, extreme fatigue, skin rashes, fever, and kidney problems. Researchers at The Scripps Research Institute have now identified the main trigger for the development of this disease.

Lupus is one of several autoimmune diseases in which the immune system turns against parts of the body, destroying the very cells and tissues it is meant to protect. In a study published in the Early Edition of the Proceedings of the National Academy of Sciences (PNAS) the week of June 29, 2009, Scripps Research Professor of Immunology and Microbial Science Dwight Kono and colleagues demonstrate that three proteins, called Toll-like receptors (TLRs), are necessary for this autodestruction to occur. TLRs may thus provide effective targets for the development of new treatments for lupus, as well as other autoimmune diseases.

http://www.sciencedaily.com/releases/2009/06/090629200811.htm
Thanks for this as I am dealing with my mom's Lupus too! Glad I could be of some help...bump Good post Thanks Lynn
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