Hi All...I will be receiving my first infusion of remicade on Monday, however I usually take my mtx on Sunday evening. Do you know if it's ok to take them that close together? I am not sure that I can reach my rheumy on a Sunday. I know, I know, I should have asked her a while ago. Help and thanks....... I Take both, don't think there will be a problem, the Rd has never told me I shoudn't.Good Luck..by the way the infusions have never been a problem for me.. The first one gave me a burst of energy! now sometimes it will make me a little tired.. but it has really helped :-)Thank you Janlee, that's encouraging! Happy Sunday....... Hi GG and Janlee! I was just wondering how bad you still were physically when your Rheumatologists decided to put you on Remicade. I know my rheumatologist is considering it. I am currently on 15 mg methotrexate, 5 mg prednisone, and 400 plaquenil. I still have some swelling in my knuckles and wrists. My joints still ache (but I'm not sure why - maybe its some of the meds.) My numbers still show some inflammation, too. I am not sure if I should increase the methotrexate or start on Remicade. Any thoughts? What dose of methotrexate are you on? How bad off were you when you added the Remicade??? Thanks. Kimpksmdrag, I was on 15mg of MTX when I started treatment, Rd increased to 7 a week after 2 months after a total of 6 months, remicade was introduced..my inflamation levels were down, but I was still having some pain in my hands & feet... I resisted going on the remicade at first thinking I wasn't doing so bad, but Rd really wanted me to. so I decided if insurance would cover I would give it a try. 1 yr later I'm not having hardly any pain.. I'm doing great.. in fact my treatments are 10 weeks instead of 8 and will be increased more as long as I am doing good.. something I didn't know was I may be able to get off Remicade if I can go 12 weeks without a treatment!!