Alternate Therapy | Arthritis Information

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I thought I would share this information with you.   I am still on a learning curve.

A couple of weeks ago I was asked this question via our website

"My query is based on the fact that one of the ways of using corticosteroids in other chronic conditions is to use double the daily dose but taken on alternate days - hence the name alternate day therapy. It is believed to mimic the diurnal variation of cortisol production in the body better and is associated with fewer longterm side-effects. I had gathered from the website that you are all non-medical people but I wondered if your nice consultant had ever said anything about it."

I asked my excellent Rheumy ( I do not know how I would have got through all of this without my two brilliant GPs and two Excellent Consultant Rheumatogolists) and this was the response'

"Yes, I often tell patients to take alternate days as the suppressing effect on the adrenal glands is minimal. I usually do this only when the dose is below 10mg prednisolone. If any one needs higher doses, whatever the advantages in terms of side-effects, the PMR or GCA often needs the steroids daily".


Please note 10mg prednisolone is the key


This information could be of some use when trying to get down and not having to cut the tablets in half or use the non-enteric coated 1mg.

But remember, never do anything without consulting either your GP or Rheumatologist. We are all different in someways.


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