I just started Orencia again and I am experiencing painful periods. I went to the OB/GYN because the pain was really back for two days around my ovaries. They did an ultrasound and I am waiting on the results. I swear the 10 months I was off this biologic I didn't experience this much pain. I curious to know if anyone else out there has had this kind of problem. I don't know if I can go through this every month with out taking pain killers.