Women's risk of developing autoimmune rheumatic disease increases incrementally according to the frequency and duration of their exposure to insecticides, a large observational study suggested.
The study of almost 77,000 women found that those who personally mixed or applied insecticides had an adjusted hazard ratio for rheumatoid arthritis or systemic lupus erythematosus of 1.57 (95% CI 1.18 to 2.11) when compared women who reported no exposure to the chemicals, according to Christine G. Parks, PhD, of the National Institute for Environmental Health Science in Durham, N.C., and colleagues.
Moreover, the adjusted hazard ratio rose to 1.97 (95% CI 1.20 to 3.23, P=0.003) with 20 or more years of exposure and to 2.04 (95% CI 1.17 to 3.56, P=0.003) with six or more exposures per year, Parks and colleagues reported in the February Arthritis Care & Research.
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The study of almost 77,000 women found that those who personally mixed or applied insecticides had an adjusted hazard ratio for rheumatoid arthritis or systemic lupus erythematosus of 1.57 (95% CI 1.18 to 2.11) when compared women who reported no exposure to the chemicals, according to Christine G. Parks, PhD, of the National Institute for Environmental Health Science in Durham, N.C., and colleagues.
Moreover, the adjusted hazard ratio rose to 1.97 (95% CI 1.20 to 3.23, P=0.003) with 20 or more years of exposure and to 2.04 (95% CI 1.17 to 3.56, P=0.003) with six or more exposures per year, Parks and colleagues reported in the February Arthritis Care & Research.
To read the rest of the article:
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