can mtx make you worse | Arthritis Information

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Has anyone had increased joint pain or flares right after taking MTX?Wow, what a  thought!  Nope, not so far.  Only been on mtx sinced diagnosed in August.  Sure will be interesting to hear if anyone has had  any issues! it seems that I have flared right after the injections at least 2x now...2 weeks ago my thumb flared up the day after my mtx pills, but maybe if I didn't take the pills it would have been more than my thumb, so it's hard to count that as evidence, I guess.

yes, i did when i was taking the pill form for 3 months almost 4 months. It worked good the first month or so, and then I went downhill fast. i actually got worse debilitated me, i was actually bed ridden.

it is an uncommon reaction according to my pcp & rd, but does happen... that is why I am not on MTX w/Humira. I had increased joint swelling (my right knee swelled to a grapefruit size, no joke) had 2 x-rays done on it to see why it was swelling like that, lots and lots of pain, and lots and lots of gelling and stiffness, and inmobility. My PCP was surprised I did not react better to MTX, and was disappointed... so he sent me back to an RD.

Told my RD of my reaction and he said he had had a few to have  reaction like that to MTX.

I believe it was what made me worse, because after I stopped taking it, I got a little better. Even though one person on the boards did not believe that MTX could make you worse. You know who you are.

I also did not have any side effects like most do when they take MTX, like sick the next day or feel drained. I was just the same as before I took my doses.

 

Crunchy,  I had HORRIBLE muscle pain and weakness after mtx.  That is why I was taken off of it after several tries. I did... I was almost in bed and couldn't walk down the stairs and I hated going outside because what it did with being sun sensitive.  I hated MXT
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