mtx and mouth ulcers | Arthritis Information

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Hi there,
How long after you start taking MTX would you expect to see mouth ulcers?
Folic Acid works wonders for mouth ulcers.  Sorry I can't answer your question but if I'm not taking the folic acid....it isn't long.  They hurt.Ditto on the folic acid.I'd think it would be pretty soon if you were going to get one. Not everyone gets them.....and some hvae them really bad. They aren't much fun!

Hi Chris,

it depends on how much mxt you are taking and to avoid that you should tak folidacid as other members said

 

Does the folic acid stop them for sure?

no. I actually spent two years on MTX without taking it and although I got them......I still get them just about as much as before. I kindof think some people are prone to get them and some aren't. I had a horrible time with them when I was young also and it had nothing to do with MTX at all.

It's definately a good idea to take the Folic Acid to relieve many of the side effects of MTX but it won't totally stop you from getting them all together.

 

Ditto, Lovie.  Sometimes I can go for long periods w/o taking the folic acid (stubborn man syndrome) and I won't get the mouth sores, then all of a sudden they return.  It takes a while of course, but the folic acid gets rid of them.

 

I went several months on mtx without mouth sores, and I've been on 4mgs Folic Acid a day since my second week on mtx.  After one of many Mtx dosage increases I developed a sore on around day 3 after taking my weekly Mtx dose.  I am not sure how bad these things can get, but mine were not too bad, however doc tells me I have a high pain threshold too.  I had a small one on my lip that went away after a few days, then one my tongue a day or two later that also went away after a few days.  Then the lip again.  These things were nothing compared to the fever blisters my daughter gets.  When I talked with the doc at my next visit she gave me a script for Leucovorin.  Told me to stop Folic Acid on the day of my Mtx and take the Leucovorin (1 tab 3x a day on Mtx day only.)  It seems to have worked.  I have not had any more sores.

Hope this helps!

I get mouth sores every once in a while.  I got them before I started MTX, though.  I haven't really noticed that I get them more frequently than before MTX.

Like dgeg1212, I also take Leucovorin (folinic acid).  I take 10mg (which is 2 tabs) the same time I take my MTX.  I don't take folic acid except for the amount I get in my multivitamin (433mcg).  I've always taken Leucovorin as my doctor prescribed it for me at the same time he started me on MTX.  I don't have any noticeable side effects from the MTX, so I think the Lecovorin must be doing its job!

dordale :)
I don't get mouth sores from MXT.  I take 4mg. Folic and also use a hydrogen peroxide mouth rinse.  Not everyone gets them.  Maybe you'll be lucky like me. 
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